Functional connection between histone acetyltransferase Gcn5p and methyltransferase Hmt1p
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Functional connection between histone acetyltransferase Gcn5p and methyltransferase Hmt1p.
Histone acetylation and methylation are linked to a variety of nuclear activities, most notably transcriptional regulation. Both synergistic and antagonistic relationships between these two modifications have been reported in different systems. Here we show that the budding yeast histone H4 arginine 3 (R3) methyltransferase Hmt1p binds acetylated histones H3 and H4, and importantly, that acetyl...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
سال: 2009
ISSN: 1874-9399
DOI: 10.1016/j.bbagrm.2009.03.004